| Sawmills Elementary | Caldwell County Schools | Granite Falls | PK-5 | 351 | 17.2:1 |
| SCALE School | Guilford County Schools | Greensboro | 6-12 | 15 | 1.6:1 |
| SCORE Academy | Wake County Schools | Cary | 9-12 | 584 | 18.3:1 |
| Scotland Early College High | Scotland County Schools | Laurinburg | 9-13 | 238 | 21.3:1 |
| Scotland High School | Scotland County Schools | Laurinburg | 9-12 | 1,294 | 15.5:1 |
| Scotland Neck Elementary Leadership Acad | Halifax County Schools | Scotland Neck | PK-5 | 140 | 14.0:1 |
| Scotts Creek School | Jackson County Public Schools | Sylva | PK-8 | 422 | 14.7:1 |
| Scotts Elementary | Iredell-Statesville Schools | Statesville | PK-5 | 283 | 11.3:1 |
| Scotts Ridge Elementary | Wake County Schools | Apex | PK-5 | 869 | 15.3:1 |
| Scroggs Elementary | Chapel Hill-Carrboro City Schools | Chapel Hill | PK-5 | 410 | 12.1:1 |
| Scurlock Elementary | Hoke County Schools | Raeford | PK-5 | 611 | 15.3:1 |
| SEA-Tech | New Hanover County Schools | Castle Hayne | 9-13 | 227 | 13.7:1 |
| Seaforth High | Chatham County Schools | Pittsboro | 9-12 | 1,088 | 19.1:1 |
| Seagrove Elementary School | Randolph County School System | Seagrove | K-5 | 332 | 13.8:1 |
| Seawell Elementary | Chapel Hill-Carrboro City Schools | Chapel Hill | PK-5 | 416 | 12.4:1 |
| Sedalia Elementary | Guilford County Schools | Sedalia | PK-5 | 535 | 14.7:1 |
| Sedge Garden Elementary | Winston Salem / Forsyth County Schools | Kernersville | PK-5 | 714 | 14.3:1 |
| Sedgefield Elementary | Guilford County Schools | Greensboro | PK-5 | 489 | 15.8:1 |
| Sedgefield Middle | Charlotte-Mecklenburg Schools | Charlotte | 6-8 | 534 | 18.7:1 |
| Sedgefield Montessori | Charlotte-Mecklenburg Schools | Charlotte | PK-6 | 485 | 13.3:1 |
| Selma Burke Middle | Mooresville Graded School District | Mooresville | 6-8 | 649 | 17.1:1 |
| Selma Elementary | Johnston County Public Schools | Selma | PK-5 | 794 | 12.6:1 |
| Selma Middle School | Johnston County Public Schools | Selma | 6-8 | 339 | 10.0:1 |
| Selwyn Elementary | Charlotte-Mecklenburg Schools | Charlotte | K-5 | 669 | 14.2:1 |
| Seventy-First Classical Middle | Cumberland County Schools | Fayetteville | 6-8 | 433 | 14.4:1 |
| Seventy-First High | Cumberland County Schools | Fayetteville | 9-12 | 1,332 | 24.0:1 |
| Shady Brook Elementary | Kannapolis City Schools | Kannapolis | K-5 | 322 | 14.0:1 |
| Shady Grove Elementary | Davie County Schools | Advance | PK-5 | 492 | 15.9:1 |
| Shadybrook Elementary | Guilford County Schools | High Point | PK-5 | 319 | 13.2:1 |
| Shallotte Middle | Brunswick County Schools | Shallotte | 6-8 | 627 | 16.4:1 |
| Shamrock Gardens Elementary | Charlotte-Mecklenburg Schools | Charlotte | PK-5 | 532 | 14.1:1 |
| Sharon Elementary | Iredell-Statesville Schools | Statesville | PK-5 | 251 | 13.6:1 |
| Sharon Elementary | Charlotte-Mecklenburg Schools | Charlotte | K-5 | 688 | 16.4:1 |
| Shaw Academy | Scotland County Schools | Laurinburg | 6-12 | 122 | 10.6:1 |
| Shawboro Elementary School | Currituck County Schools | Shawboro | PK-5 | 625 | 16.1:1 |
| Sheep-Harney Elementary | Elizabeth City-Pasquotank Public Schools | Elizabeth City | PK-5 | 441 | 16.1:1 |
| Shelby High | Cleveland County Schools | Shelby | 9-12 | 792 | 15.4:1 |
| Shelby Middle | Cleveland County Schools | Shelby | 6-8 | 588 | 16.6:1 |
| Shepherd Elementary | Iredell-Statesville Schools | Mooresville | PK-5 | 738 | 15.7:1 |
| Sherrills Ford Elementary | Catawba County Schools | Sherrills Ford | K-6 | 633 | 17.9:1 |
| Sherwood Elementary | Gaston County Schools | Gastonia | PK-5 | 553 | 16.4:1 |
| Sherwood Forest Elementary | Winston Salem / Forsyth County Schools | Winston Salem | PK-5 | 670 | 15.2:1 |
| Sherwood Githens Middle | Durham Public Schools | Durham | 6-8 | 878 | 17.1:1 |
| Sherwood Park Elementary | Cumberland County Schools | Fayetteville | PK-5 | 335 | 12.1:1 |
| Shiloh Valley Elementary | Union County Public Schools | Monroe | 3-5 | 574 | 16.4:1 |
| Shiloh Valley Primary School | Union County Public Schools | Monroe | PK-2 | 563 | 13.3:1 |
| Shining Rock Classical AcademyCharter | Shining Rock Classical Academy | Waynesville | K-12 | 616 | 13.0:1 |
| Shive Elementary | Rowan-Salisbury Schools | Rockwell | PK-5 | 413 | 14.5:1 |
| Shoals Elementary | Surry County Schools | Pinnacle | PK-5 | 235 | 13.4:1 |
| Shuford Elementary | Newton Conover City Schools | Conover | K-5 | 402 | 15.1:1 |
| Siler City Elementary | Chatham County Schools | Siler City | PK-5 | 591 | 12.3:1 |
| Silk Hope School | Chatham County Schools | Siler City | PK-8 | 281 | 13.2:1 |
| SILSA | Asheville City Schools | Asheville | 9-12 | 332 | 24.0:1 |
| Silver Valley Elementary | Davidson County Schools | Lexington | PK-5 | 221 | 12.4:1 |
| Silverdale Elementary | Onslow County Schools | Maysville | K-5 | 648 | 15.8:1 |
| Smith Elementary | Wake County Schools | Raleigh | PK-5 | 596 | 13.0:1 |
| Smith Farm Elementary | Winston Salem / Forsyth County Schools | Winston-Salem | PK-5 | 440 | 12.1:1 |
| Smith Middle | Chapel Hill-Carrboro City Schools | Chapel Hill | 6-8 | 763 | 13.7:1 |
| Smithfield Elementary | Charlotte-Mecklenburg Schools | Charlotte | PK-5 | 672 | 16.6:1 |
| Smithfield Middle | Johnston County Public Schools | Smithfield | 6-8 | 573 | 13.2:1 |
| Smithfield-Selma High | Johnston County Public Schools | Smithfield | 9-12 | 1,548 | 17.9:1 |
| Smokey Mountain Elementary | Jackson County Public Schools | Whittier | PK-8 | 340 | 15.8:1 |
| Smoky Mountain High School | Jackson County Public Schools | Sylva | 9-12 | 881 | 21.2:1 |
| Snow Creek Elementary | Catawba County Schools | Hickory | PK-6 | 551 | 15.2:1 |
| Snow Hill Primary | Greene County Schools | Snow Hill | K-1 | 403 | 12.6:1 |
| Socrates AcademyCharter | Socrates Academy | Matthews | K-12 | 1,039 | 19.6:1 |
| South Academy of International Languages | Charlotte-Mecklenburg Schools | Charlotte | K-8 | 1,259 | 14.8:1 |
| South Asheboro Middle | Asheboro City Schools | Asheboro | 6-8 | 491 | 15.8:1 |
| South Brunswick High | Brunswick County Schools | Southport | 9-12 | 1,154 | 17.1:1 |
| South Brunswick Middle | Brunswick County Schools | Southport | 6-8 | 585 | 16.2:1 |
| South Caldwell High | Caldwell County Schools | Hudson | 9-12 | 1,272 | 19.1:1 |
| South Central | Pitt County Schools | Winterville | 9-12 | 1,738 | 18.4:1 |
| South Charlotte Middle | Charlotte-Mecklenburg Schools | Charlotte | 6-8 | 770 | 18.9:1 |
| South Columbus High | Columbus County Schools | Tabor City | 9-12 | 669 | 15.7:1 |
| South Creek Elementary | Martin County Schools | Robersonville | PK-5 | 337 | 16.6:1 |
| South Creek Middle | Martin County Schools | Robersonville | 6-8 | 146 | 12.2:1 |
| South Davidson Middle and High | Davidson County Schools | Denton | 6-12 | 640 | 13.6:1 |
| South Davie Middle | Davie County Schools | Mocksville | 6-8 | 492 | 12.8:1 |
| South Edgecombe Middle | Edgecombe County Public Schools | Pinetops | 6-8 | 271 | 14.1:1 |
| South Elementary | Caswell County Schools | Mebane | PK-5 | 235 | 16.9:1 |
| South Elementary | Mooresville Graded School District | Mooresville | PK-2 | 466 | 13.1:1 |
| South Elementary | Person County Schools | Roxboro | PK-5 | 463 | 16.9:1 |
| South End Elementary | Rockingham County Schools | Reidsville | PK-5 | 355 | 20.9:1 |
| South Fork Elementary | Winston Salem / Forsyth County Schools | Winston Salem | PK-5 | 503 | 12.4:1 |
| South Garner High | Wake County Schools | Garner | 9-12 | 1,835 | 17.4:1 |
| South Graham Elementary | Alamance-Burlington Schools | Graham | PK-5 | 518 | 15.2:1 |
| South Granville High | Granville County Schools | Creedmoor | 9-12 | 706 | 21.4:1 |
| South Greenville Elementary | Pitt County Schools | Greenville | PK-5 | 251 | 9.8:1 |
| South Harnett Elementary | Harnett County Schools | Bunnlevel | 3-5 | 476 | 14.2:1 |
| South Iredell High | Iredell-Statesville Schools | Statesville | 9-12 | 1,768 | 21.3:1 |
| South Johnson Elementary | Scotland County Schools | Laurinburg | PK-5 | 654 | 13.9:1 |
| South Johnston High | Johnston County Public Schools | Four Oaks | 9-12 | 1,355 | 22.5:1 |
| South Lakes Elementary | Wake County Schools | Fuquay-Varina | PK-5 | 774 | 14.9:1 |
| South Lenoir High | Lenoir County Public Schools | Deep Run | 9-12 | 721 | 15.2:1 |
| South Lexington Developmental Center | Lexington City Schools | Lexington | K-12 | 26 | 8.3:1 |
| South Lexington School | Lexington City Schools | Lexington | PK-K | 308 | 13.0:1 |
| South Macon Elementary | Macon County Schools | Franklin | PK-4 | 465 | 13.9:1 |
| South Mebane Elementary | Alamance-Burlington Schools | Mebane | K-5 | 506 | 16.4:1 |
| South Mecklenburg High School | Charlotte-Mecklenburg Schools | Charlotte | 9-12 | 2,534 | 17.8:1 |
| South Newton Elementary | Newton Conover City Schools | Newton | PK-5 | 328 | 14.7:1 |
| South Pine Academy | Charlotte-Mecklenburg Schools | Charlotte | PK-5 | 765 | 18.9:1 |
| South Point High | Gaston County Schools | Belmont | 9-12 | 989 | 18.2:1 |
| South Providence | Union County Public Schools | Waxhaw | 6-12 | 91 | 4.4:1 |
| South Robeson Middle School | Public Schools of Robeson County | Rowland | 6-8 | 344 | 15.4:1 |
| South Rowan High | Rowan-Salisbury Schools | China Grove | 9-12 | 932 | 21.5:1 |
| South Smithfield Elementary | Johnston County Public Schools | Smithfield | PK-5 | 450 | 12.4:1 |
| South Stanly High | Stanly County Schools | Norwood | 9-12 | 442 | 16.3:1 |
| South Stanly Middle | Stanly County Schools | Norwood | 6-8 | 402 | 17.0:1 |
| South Stokes High School | Stokes County Schools | Walnut Cove | 9-12 | 538 | 14.5:1 |
| South Toe Elementary | Yancey County Schools | Burnsville | K-5 | 107 | 12.9:1 |
| South Topsail Elementary | Pender County Schools | Hampstead | PK-5 | 618 | 16.1:1 |
| South View High | Cumberland County Schools | Hope Mills | 9-12 | 1,461 | 22.3:1 |
| South View Middle | Cumberland County Schools | Hope Mills | 6-8 | 614 | 15.8:1 |
| Southeast Alamance High | Alamance-Burlington Schools | Haw River | 9-12 | 1,079 | 19.4:1 |
| Southeast Elementary | Lenoir County Public Schools | Kinston | PK-5 | 326 | 13.6:1 |
| Southeast Guilford High | Guilford County Schools | Greensboro | 9-12 | 1,209 | 15.6:1 |
| Southeast Guilford Middle | Guilford County Schools | Greensboro | 6-8 | 826 | 16.9:1 |
| Southeast Halifax Collegiate Prep Academ | Halifax County Schools | Halifax | 9-12 | 204 | 10.2:1 |
| Southeast Middle | Winston Salem / Forsyth County Schools | Kernersville | 6-8 | 733 | 15.9:1 |
| Southeast Middle | Rowan-Salisbury Schools | Salisbury | 6-8 | 628 | 18.2:1 |